Educational content only. Not medical advice, and no doctor-patient relationship is created. Read the medical disclaimer
Peptide · GHRH analog
Sermorelin
Also known as: GRF 1-29
A short GHRH analog that encourages your pituitary to release its own growth hormone in natural pulses.
Tier 1 · Prescribe today
Grade C · Limited human evidence
Educational content only, not medical advice. Discussion here does not mean this therapy is prescribed by Youthful Medicine or available to you. Read the medical disclaimer
U.S. regulatory status
Lawfully compounded by licensed 503A pharmacies with a prescription; never placed on FDA’s Category 2 list. The original brand was withdrawn for business reasons, not safety.
What it is
The first 29 amino acids of GHRH, the active portion of the brain’s natural growth-hormone signal.
How it is thought to work
It stimulates growth hormone release while keeping pituitary feedback intact, so the body keeps its own brakes.
Animations simplify biology for teaching. They are not a claim that this peptide works this way in people.
What the research shows
Older trials in children with growth hormone deficiency and small studies in adults show higher GH and IGF-1. Effects on body composition and aging in healthy adults are modest and less certain.
Safety and considerations
Injection-site reactions, flushing and headache. Not for people with active cancer. IGF-1 should be monitored.
Our position
Our lawful growth-hormone-axis option, used to support the body’s rhythm rather than replace it.
Video lesson
AT A GLANCE
Quadrant
Hormonal Optimization
Tier
Tier 1 · Prescribe today
Evidence grade
Grade C · Limited human evidence
Last reviewed
Is this right for you?
Only a physician who has evaluated you can answer that. Consultations are with licensed Youthful Medicine providers.
Never use products labeled “research use only” or “not for human use.” Purity, dose and sterility are unverified.