Educational content only. Not medical advice, and no doctor-patient relationship is created. Read the medical disclaimer
Peptide · EPO-derived
ARA-290 (Cibinetide)
Also known as: Cibinetide
An erythropoietin-derived peptide studied for nerve pain, without EPO’s effect on red blood cells.
Tier 3 · Education only
Grade C · Limited human evidence
Educational content only, not medical advice. Discussion here does not mean this therapy is prescribed by Youthful Medicine or available to you. Read the medical disclaimer
U.S. regulatory status
Investigational; not FDA-approved. Not available outside research.
What it is
An 11-amino-acid peptide modeled on part of the hormone erythropoietin.
How it is thought to work
It activates the “innate repair receptor,” calming inflammation and supporting small nerve fibers.
Animations simplify biology for teaching. They are not a claim that this peptide works this way in people.
What the research shows
Small phase 2 trials in sarcoidosis-related small fiber neuropathy and diabetic neuropathy showed improvements in symptoms and nerve fiber measures.
Safety and considerations
Well tolerated in small trials. Larger studies are needed.
Our position
Education only, and of real interest for neuropathic pain.
Video lesson
AT A GLANCE
Quadrant
Regenerative & Cellular Health
Sub-pillar
Structural Repair
Tier
Tier 3 · Education only
Evidence grade
Grade C · Limited human evidence
Last reviewed
Is this right for you?
Only a physician who has evaluated you can answer that. Consultations are with licensed Youthful Medicine providers.
Never use products labeled “research use only” or “not for human use.” Purity, dose and sterility are unverified.